Liposome Technology
What are liposomes?
Liposomes are small spherical vesicles composed of one or more phospholipid bilayers that closely resemble natural cell membranes. They can encapsulate both hydrophilic (water-soluble) and hydrophobic (fat-soluble) substances, making them versatile carriers for a variety of applications, especially in drug delivery.
Structure of liposomes
Phospholipid bilayer: this bilayer forms the outer shell of the liposome and provides a hydrophobic barrier that can trap hydrophilic substances inside.
Aqueous core: the internal aqueous region can contain hydrophilic molecules.
Hydrophobic zone: embedded within the bilayer, it can encapsulate hydrophobic drugs or substances.
Advantages of liposomes
Biocompatible and biodegradable: liposomes are made from natural phospholipids and are safe and easily metabolized by the body.
Versatility: capable of encapsulating both hydrophilic and hydrophobic substances.
Controlled release: they can be designed to release their payload at a specific time.
Targeted Delivery: Surface modification allows for targeted delivery to specific tissues or cells, thereby minimizing off-target effects.